METALLOTHIONEINS IN SPONTANEOUSLY HYPERTENSIVE RAT LIVER
نویسندگان
چکیده
منابع مشابه
Spontaneously Hypertensive Rat Arteries
The possible role of endothelium in the vascular responses to vasodilator drugs was studied in relation to experimental hypertension. Short ring segments of the thoracic aorta and femoral artery were removed from spontaneously hypertensive rats (SHR) and normotensive WistarKyoto (WKY) rats. They were rubbed on the intimal surface to destruct endothelial cells or unrubbed, and bathed in Krebs-bi...
متن کاملHormones in the Spontaneously Hypertensive Rat
In young (4-week-old) male and female spontaneously hypertensive (SH) rats, ethanol metabolic rate in vivo and hepatic alcohol dehydrogenase activity in vitro are high and not different in the two sexes. In males, ethanol metabolic rate falls markedly between 4 and 10 weeks of age, which coincides with the time of development of sexual maturity in the rat. Alcohol dehydrogenase activity is also...
متن کاملVascular Reactivity in the Spontaneously Hypertensive Rat
The role of extracellular calcium and high blood pressure stress in altered vascular adrenergic responsiveness in rings of femoral artery from spontaneously hypertensive rats (SHR) was investigated. A model in which partial ligation of the external iliac artery prevents the increase in blood pressure to the ipsilateral femoral artery was used to assess the effect of the increase in pressure str...
متن کاملVesicovascular reflexes in the spontaneously hypertensive rat.
AIMS We investigated the effects of hypertension and acute blood pressure changes on rats' vesicovascular reflexes (VVRs). MAIN METHODS Twelve-week-old male Wistar rats and spontaneously hypertensive rats (SHRs) were anesthetized with urethane, and underwent real-time cystometry and blood pressure monitoring. The SHRs were administered nifedipine or valsartan intravenously. The Wistar rats we...
متن کاملGenetic heterogeneity of the spontaneously hypertensive rat.
We examined DNA fingerprints of the spontaneously hypertensive rat from Shimane Institute of Health Science, Izumo, Japan, including seven substrains that were separated in the early stages of the establishment of the stroke-prone spontaneously hypertensive rat, and compared their fingerprints with those of rats from other sources. Obtained DNA fingerprints revealed that, in both the stroke-res...
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ژورنال
عنوان ژورنال: Japanese Journal of Medical Science and Biology
سال: 1992
ISSN: 0021-5112,1884-2828
DOI: 10.7883/yoken1952.45.185